Hi, I’m currently a Ph.D. candidate study in Immunology and Computational Biology in Purdue University, West Lafayette.

I’m working in Dr.Qing Deng’s Lab and co-adviosred by Dr.Xiaoping Bao’s Lab. Cell and gene therapies hold great promise to treat a number of cancers and inherited genetic disorders, including leukemia, Cancer, Duchenne Muscular Dystrophy (DMD), etc. Right now, the remarkable potential of neutrophil engineering for targeted therapies is exciting. My research focuses on developing human iPSC-derived neutrophils and engineered neutrophil platforms for cancer immunotherapy, with particular interests in CAR-neutrophil therapy and in vivo immune cell engineering. My work integrates human pluripotent stem cell differentiation, CRISPR/Cas9 genome engineering, viral vector engineering, multi color flow cytometry, molecular characterization, immune cell functional assays, and in vivo models to understand and improve neutrophil development and therapeutic function. I am particularly interested in how engineered immune cells can be systematically designed, characterized, and optimized for the treatment of solid tumors. Additionally, I am also interested in leveraging advanced machine learning models and AI-driven approaches to screen for the most effective CAR structures tailored specifically for neutrophils. These efforts represent our commitment to integrating AI for scientific discovery, enhancing the precision and efficacy of targeted therapies in the fight against complex diseases.